Meanwhile the capture of Tunis had made patent to all Europe how deep was the wound that the credit and power of the Ottoman Empire had received at Lepanto. This great defeat was no doubt a disaster for the Turks; but a glorious disaster, both on account of the deeds of valour they had performed, and the titanic efforts it cost the victors to gain the triumph. The flight from Tunis without firing a shot, at the mere presence of D. John two years after this rude warning, showed how deeply rooted was the terror in the souls of the infidels, and how the renown of the Christian bravery had been enhanced, especially that of the Spaniards. All this cruelly wounded the overweening pride of Selim, and he was consumed with the desire of avenging himself by reconquering Tunis and Goletta. He was urged, with malicious eagerness, to undertake this enterprise by Aluch Ali and the renegade Mustafa, one of the engineers who built Goletta in the time of Charles V. The name of this traitor was Jacobo Zitolomini. Resenting the treatment he had received from Philip II, he fled to Algiers to Aluch Ali, who took him to Constantinople, where he revealed to Selim a sure and secret way of taking Goletta.

At the beginning of May, 1574, D. John received an urgent message from Gabrio Cervelloni, to say that the Turks were preparing a very powerful fleet; that it was feared that they would fall suddenly upon Tunis, and that, in consequence of this, funds should be sent as quickly as possible to finish the new fort, which was not yet completed. D. John was at Genoa, quieting the disturbances there, and he hastened to send the Commissary of the Fleet Juan de Soto to Madrid, to warn Philip II of the danger which threatened. The King was not much alarmed about this, and, perhaps, saw a prompt and certain opportunity of ridding himself of this care and worry of Tunis. At any rate, his answer makes it clear that this new conquest was the least of his cares, and while writing to Cardinal Granvelle, Viceroy of Naples, and to the Duque de Terranova, Regent of Sicily, that they were to guard the ports and reinforce the garrisons, especially in Messina, Augusta, Syracuse, Trapani and Palermo, he contented himself with adding that they were not to forget to help his brother, and to look after the coast of Barbary. He also ordered D. García de Toledo and the Marqués de Santa Cruz to watch how D. John was garrisoning Goletta, and to the latter the King wrote that he was to do what he judged best in the matter, but that he was to remember that he had said that 2000 foot soldiers were enough to defend Goletta. D. John then sent D. Juan de Cardona with all the galleys under his command to Tunis without loss of time, taking the help for which Gabrio Cervelloni craved. This was not sufficient, and those in Tunis reiterated their request. D. John then exhausted all his resources, and sent D. Bernardino de Velasco with twenty Neapolitan galleys and four companies of Italian infantry. With these comings and goings summer was getting old, and on the 13th of August, at the Cape of Carthage, appeared the dreaded Turkish fleet of 300 ships and 60,000 soldiers, the fleet being commanded by Aluch Ali, and the troops by Selim's son-in-law Sinan Pasha, the renegade.

A great outcry arose at the extreme peril of the Barbary Christians, and by every means in their power they sent to ask help from Granvelle, Terranova, and, above all, from D. John of Austria, in virtue of his office and Christian piety. He wished to fly to their aid, abandoning everything. He wrote first, however, to the Duque de Sesa, "To urge the Cardinal to send people to help Goletta, as that province was in his charge." But the imperturbable Granvelle replied coldly, "That he had much to guard in the Kingdom, and that it did not suit him to divide his forces." "This was," says Vander Hammen, commenting on the fact, "to give colour to the excuse. The real reason was Granvelle's dislike to support D. John, jealous of his favours with Mars and Venus, and because he was a foreigner, and because his brothers conspired in the Flemish rebellion;" and Luis Cabrera de Córdoba expresses himself in similar words, equally severe, not forgetting Mars and Venus. And D. John himself wrote to his sister Donna Margarita: "In short, Lady, everything goes badly; and in truth it is not entirely the fault of His Majesty, except for permitting those who govern his States to forget that those in their vicinity, or those that are not, are as much His Majesty's as those which each minister has charge of."

Meanwhile D. John, tired of waiting for orders, troops and money which did not come, and making it a point of honour to go to Tunis, moved with desperate activity from Genoa to Naples, Messina and Palermo, recruiting soldiers everywhere, chartering ships, and pledging for all this his plate, his jewels, and even his word, until he had collected at Messina a moderate fleet with no lack of fighting men. He was all ready to sail for Africa, when he met with another obstacle, more powerful than the calculated coldness of Philip II, or the jealous hatred of the Cardinal. The sea! The terrible sea which rose in a furious storm which threw him to Trapani, much against his will, and kept him there days and days, giving time for Christians to perish and for the Turks to become victorious. Three times he tried to leave the port, defying the storm, and as often had to retire before the surging waves. Then he sent four galleys without quarter-decks and platforms on the forecastles to take the mere hope of help to Goletta, but the implacable tempest prevented this by destroying two of them. At last the weather improved; but before D. John could put to sea, a French galley, without masts and knocked about by the storm, was driven int............