From the marrow we pass on in natural sequence to the brain. For there are many who think that the brain itself consists of marrow, and that it forms the commencement of that substance, because they see that the spinal marrow is continuous with it. In reality the two may be said to be utterly opposite to each other in character. For of all the parts of the body there is none so cold as the brain; whereas the marrow is of a hot nature, as is plainly shown by its fat and unctuous character. Indeed this is the very reason why the brain and spinal marrow are continuous with each other. For, wherever the action of any part is in excess, nature so contrives as to set by it another part with an excess of contrary action, so that the excesses of the two may counterbalance each other. Now that the marrow is hot is clearly shown by many indications. The coldness of the brain is also manifest enough. For in the first place it is cold even to the touch; and, secondly, of all the fluid parts of the body it is the driest and the one that has the least blood; for in fact it has no blood at all in its proper substance. This brain is not residual matter, nor yet is it one of the parts which are anatomically continuous with each other; but it has a character peculiar to itself, as might indeed be expected. That it has no continuity with the organs of sense is plain from simple inspection, and is still more clearly shown by the fact, that, when it is touched, no sensation is produced; in which respect it resembles the blood of animals and their excrement. The purpose of its presence in animals is no less than the preservation of the whole body. For some writers assert that the soul is fire or some such force. This, however, is but a rough and inaccurate assertion; and it would perhaps be better to say that the soul is incorporate in some substance of a fiery character. The reason for this being so is that of all substances there is none so suitable for ministering to the operations of the soul as that which is possessed of heat. For nutrition and the imparting of motion are offices of the soul, and it is by heat that these are most readily effected. To say then that the soul is fire is much the same thing as to confound the auger or the saw with the carpenter or his craft, simply because the work is wrought by the two in conjunction. So far then this much is plain, that all animals must necessarily have a certain amount of heat. But as all influences require to be counterbalanced, so that they may be reduced to moderation and brought to the mean (for in the mean, and not in either extreme, lies the true and rational position), nature has contrived the brain as a counterpoise to the region of the heart with its contained heat, and has given it to animals to moderate the latter, combining in it the properties of earth and water. For this reason it is, that every sanguineous animal has a brain; whereas no bloodless creature has such an organ, unless indeed it be, as the Poulp, by analogy. For where there is no blood, there in consequence there is but little heat. The brain, then, tempers the heat and seething of the heart. In order, however, that it may not itself be absolutely without heat, but may have a moderate amount, branches run from both blood-vessels, that is to say from the great vessel and from what is called the aorta, and end in the membrane which surrounds the brain; while at the same time, in order to prevent any injury from the heat, these encompassing vessels, instead of being few and large, are numerous and small, and their blood scanty and clear, instead of being abundant and thick. We can now understand why defluxions have their origin in the head, and occur whenever the parts about the brain have more than a due proportion of coldness. For when the nutriment steams upwards through the blood-vessels, its refuse portion is chilled by the influence of this region, and forms defluxions of phlegm and serum. We must suppose, to compare small things with great, that the like happens here as occurs in the production of............