The point for consideration next in order to the preceding is:-What are the processes in which the affection of waking and sleeping originates, and whence do they arise? Now, since it is when it has sense-perception that an animal must first take food and receive growth, and in all cases food in its ultimate form is, in sanguineous animals, the natural substance blood, or, in bloodless animals, that which is analogous to this; and since the veins are the place of the blood, while the origin of these is the heart-an assertion which is proved by anatomy-it is manifest that, when the external nutriment enters the parts fitted for its reception, the evaporation arising from it enters into the veins, and there, undergoing a change, is converted into blood, and makes its way to their source [the heart]. We have treated of all this when discussing the subject of nutrition, but must here recapitulate what was there said, in order that we may obtain a scientific view of the beginnings of the process, and come to know what exactly happens to the primary organ of sense-perception to account for the occurrence of waking and sleep. For sleep, as has been shown, is not any given impotence of the perceptive faculty; for unconsciousness, a certain form of asphyxia, and swooning, all produce such impotence. Moreover it is an established fact that some persons in a profound trance have still had the imaginative faculty in play. This last point, indeed, gives rise to a difficulty; for if it is conceivable that one who had swooned should in this state fall asleep, the phantasm also which then presented itself to his mind might be regarded as a dream. Persons, too, who have fallen into a deep trance, and have come to be regarded as dead, say many things while in this condition. The same view, however, is to be taken of all these cases, [i.e. that they are not cases of sleeping or dreaming].

As we observed above, sleep is not co-extensive with any and every impotence of the perceptive faculty, but this affection is one which arises from the evaporation attendant upon the process of nutrition. The matter evaporated must be driven onwards to a certain point, then turn back, and change its current to and fro, like a tide-race in a narrow strait. Now, in every animal the hot naturally tends to move [and carry other things] upwards, but when it has reached the parts above [becoming cool], it turns back again, and moves downwards in a mass. This explains why fits of drowsiness are especially apt to come on after meals; for the matter, both the liquid and the corporeal, which is borne upwards in a mass, is then of considerable quantity. When, therefore, this comes to a stand it weighs a person down and causes him to nod, but when it has actually sunk downwards, and by its return has repulsed the hot, sleep comes on, and the animal so affected is presently asleep. A confirmation of this appears from considering the things which induce sleep; they all, whether potable or edible, for instance poppy, mandragora, wine, darnel, produce a heaviness in the head; and persons borne down [by sleepiness] and nodding [drowsily] all seem affected in this way, i.e. they are unable to lift up the head or the eye-lids. And it is after meals especially that sleep comes on like this, for the evaporation from the foods eaten is then copious. It also follows certain forms of fatigue; for fatigue operates as a solvent, and the dissolved matter acts, if not cold, like food prior to digestion. Moreover, some kinds of illness have this same effect; those arising from moist and hot secretions, as happens with fever-patients and in cases of lethargy. Extreme youth also has this effect; infants, for example, sleep a great deal, because of the food being all borne upwards-a mark whereof appears in the disproportionately large size of the upper parts compared with the lower during infancy, which is due to the fact that growth predominates in the direction of the former. Hence also they are subject to epileptic seizures; for sleep is like epilepsy, and, in a sense, actually is a seizure of this sort. Accordingly, the beginning of this malady takes place with many during sleep, and their subsequent habitual seizures occur in sleep, not in waking hours. For when the spirit [evaporation] moves upwards in a volume, on its return downwards it distends the veins, and forcibly compresses the passage through which respiration is effected. This explains why wines are not good for infants or for wet nurses (for it makes no difference, doubtless, whether the infants themselves, or their nurses, drink them), but such persons should drink them [if at all] diluted with water and in small quantity. For wine is spirituous, and of all wines the dark more so than any other. The upper parts, in infants, are so filled with nutriment that within five months [after birth] they do not even turn the neck [sc. to raise the head]; for in them, as in persons deeply intoxicated, there is ever a large quantity of moisture ascending. It is reasonable, too, to think that this affection is the cause of the embryo’s remaining at rest in the womb at first. Also, as a general rule, persons whose veins are inconspicuous, as well as those who are dwarf-like, or have abnormally large heads, are addicted to sleep. For in the former the veins are narrow, so that it is not easy for the moisture to flow down through them; while in the case of dwarfs and those whose heads are abnormally large, the impetus of the evaporation upwards is excessive. Those [on the contrary] whose veins are large are, thanks to the easy flow through the veins, not addicted to sleep, unless, indeed, they labour under some other affection which counteracts [this easy flow]. Nor are the ‘atrabilious’ ad............